Synthesis of Glucosyl and Mannosyl Derivatives of N-Methylmethylthiocolchicine Author: Khun-Shi Liao, George T. Shiau(Department of Chemistry, National Taiwan Normal University)

Abstract：

Four new glycosyl derivatives 7-10 of N-methyl-methylthiocblchicine have been prepared from colchicine through an intermediate N-methyl-N-deacetyl-methylthiocolchicine (6) and ex-amined by NMR and MS techniques. The water solubility of new compounds is increased due to the glycosyl mioety.

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